Altered growth hormone and prolactin responses to dopaminergic stimulation in Huntington's chorea.

@article{Caraceni1977AlteredGH,
  title={Altered growth hormone and prolactin responses to dopaminergic stimulation in Huntington's chorea.},
  author={Tommaso Caraceni and Alberto Emilio Panerai and E A Paratl and Daniela Cocchi and EugenioE. M{\"u}ller},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1977},
  volume={44 5},
  pages={
          870-5
        }
}
Seven patients affected by Huntington's chorea were given an acute administration of 2-Br-alpha-ergocryptine (CB 154, Sandoz), a direct agonist at dopamine receptor sites. Seven nonobese hospitalized patients were used as controls. Oral administration of CB 154 (2.5 mg) induced a more prompt and consistent rise in plasma growth hormone (GH) levels in patients than in controls. GH levels rose from baseline values of 0.3+/-0.1 ng/ml to mean peak values of 20.4+/-5.1 ng/ml (120-270 min) in choreic… CONTINUE READING
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