Altered gene products are associated with activation of cellular rasK genes in human lung and colon carcinomas.

@article{Der1983AlteredGP,
  title={Altered gene products are associated with activation of cellular rasK genes in human lung and colon carcinomas.},
  author={Channing J Der and Geoffrey M. Cooper},
  journal={Cell},
  year={1983},
  volume={32 1},
  pages={201-8}
}
Two lung and two colon carcinoma cell lines of human origin, which contained the same activated rasK transforming gene, expressed abnormal species of p21 that were distinct from the p21 proteins expressed in normal human cells and other human carcinomas. The abnormal species of p21 expressed by three of these cell lines were indistinguishable from each other, but differed from the abnormal p21 expressed by one lung carcinoma cell line. NIH cells transformed by DNAs of these carcinomas expressed… CONTINUE READING

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