Altered gene expression profiles in the frontal cortex of cirrhotic alcoholics.

@article{Liu2007AlteredGE,
  title={Altered gene expression profiles in the frontal cortex of cirrhotic alcoholics.},
  author={Jianwen Liu and Joanne Marie Lewohl and R. Adron Harris and Peter Ronald Dodd and R Dayne Mayfield},
  journal={Alcoholism, clinical and experimental research},
  year={2007},
  volume={31 9},
  pages={
          1460-6
        }
}
BACKGROUND Cirrhosis is the result of chronic liver disease that causes scarring and dysfunction of the liver. The disease is a common concomitant condition resulting from sustained exposure to alcohol. Heavy alcohol use results in brain damage that is generally more severe in cirrhotic compared with noncirrhotic alcoholics. We examined, at the cellular level, gene expression in the frontal cortex of cirrhotic alcoholics. METHODS Gene expression profiles were compared between cirrhotic and… CONTINUE READING
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