Altered gene expression in the dorsolateral prefrontal cortex of individuals with schizophrenia

@inproceedings{GuillozetBongaarts2014AlteredGE,
  title={Altered gene expression in the dorsolateral prefrontal cortex of individuals with schizophrenia},
  author={Angela L. Guillozet-Bongaarts and Thomas Michael Hyde and Rachel A. Dalley and Michael J Hawrylycz and Alex M. Henry and Patrick R. Hof and John G. Hohmann and Allan R. Jones and Crysline Kuan and Josh J. Royall and Enjian Shen and Beryl Swanson and Hongkui Zeng and Joel Edward Kleinman},
  booktitle={Molecular Psychiatry},
  year={2014}
}
The underlying pathology of schizophrenia (SZ) is likely as heterogeneous as its symptomatology. A variety of cortical and subcortical regions, including the prefrontal cortex, have been implicated in its pathology, and a number of genes have been identified as risk factors for disease development. We used in situ hybridization (ISH) to examine the expression of 58 genes in the dorsolateral prefrontal cortex (DLPFC, comprised of Brodmann areas 9 and 46) from 19 individuals with a premorbid… CONTINUE READING
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