Altered galectin-1 serum levels in patients diagnosed with high-grade glioma

@article{Verschuere2013AlteredGS,
  title={Altered galectin-1 serum levels in patients diagnosed with high-grade glioma},
  author={Tina Verschuere and Matthias Van Woensel and Steffen Fieuws and Florence Lefranc and V{\'e}ronique Mathieu and R{\'o}bert Kiss and Stefaan W. Van Gool and Steven De Vleeschouwer},
  journal={Journal of Neuro-Oncology},
  year={2013},
  volume={115},
  pages={9-17}
}
High-grade gliomas (HGG) are the most common and most aggressive intrinsic human brain tumors in adults. Galectin-1, a glycan-binding protein that is overexpressed in HGG, has been shown to contribute significantly to the aggressive nature of HGG. It is unknown whether increased galectin-1 expression levels are exclusively found at the tumor site or whether galectin-1 can also be detected in the serum of HGG patients. Galectin-1 serum levels were analyzed in a prospective dataset of 43 healthy… CONTINUE READING