Altered function of synovial fluid granulocytes in patients with acute inflammatory arthritis

@article{Bender1986AlteredFO,
  title={Altered function of synovial fluid granulocytes in patients with acute inflammatory arthritis},
  author={James G. Bender and Dennis E. Van Epps and Robert Searles and Ralph Williams},
  journal={Inflammation},
  year={1986},
  volume={10},
  pages={443-453}
}
In rheumatoid arthritis (RA) a chronic inflammatory state exists in which the synovial fluid is periodically filled with large numbers of polymorphonuclear leukocytes (PMNs). Oxygen radicals produced by these cells have been implicated as mediators of tissue damage and may be directly involved in the pathogenesis of RA. We examined the production of oxygen radicals by synovial fluid PMNs (SFPMNs) and peripheral blood PMNs (PB-PMNs) by measuring chemiluminescence (CL) as well as Superoxide anion… CONTINUE READING

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References

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Showing 1-10 of 18 references

Enhancement of neutrophil function as a result of prior exposure of chemotactic factors

  • D. E. VAN EPPS, M. L. GAROA
  • J. Clin. Invest
  • 1980
Highly Influential
6 Excerpts

The respiratory burst of phagocytes

  • B. M. BAmOR
  • J. Clin. Invest
  • 1984
1 Excerpt

Analysis of the bimodal chemiluminescence pattern stimulated in human neutrophils by chemotactic factors

  • J. G. BENDER, D. E. VANEPPS
  • Infect. Immun
  • 1983
1 Excerpt

Mechanism of the luminol-dependent chemiluminescence of human neutrophils

  • L. R. DE CHATELET, G. D. LONG, +4 authors M. S. COHEN
  • J. lmmunol
  • 1982
3 Excerpts

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