Altered function of murine mast cells in response to lipopolysaccharide and peptidoglycan.

@article{Ikeda2003AlteredFO,
  title={Altered function of murine mast cells in response to lipopolysaccharide and peptidoglycan.},
  author={Teruo Ikeda and Masayuki Funaba},
  journal={Immunology letters},
  year={2003},
  volume={88 1},
  pages={21-6}
}
Toll-like receptors (TLRs) recognize and signal the presence of bacterial components such as lipopolysaccharide (LPS) and peptidoglycan (PG) as a part of innate immunity. Our previous studies revealed that mast cells function as effector cells in the protection of mice against lethal enterobacterial infections. In this study, we examined both the gene expression of molecules involved in TLR signaling and the effects of LPS and PG in bone marrow-derived cultured mast cells (BMCMCs). The mRNA… CONTINUE READING
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