Altered fine structures of corneal and skeletal keratan sulfate and chondroitin/dermatan sulfate in macular corneal dystrophy.

@article{Plaas2001AlteredFS,
  title={Altered fine structures of corneal and skeletal keratan sulfate and chondroitin/dermatan sulfate in macular corneal dystrophy.},
  author={Anna Plaas and Leigh Ann West and Eugene J-M A Thonar and Zeynel A. Karcioglu and Christopher J. S. Smith and Gordon K. Klintworth and Vincent C. Hascall},
  journal={The Journal of biological chemistry},
  year={2001},
  volume={276 43},
  pages={
          39788-96
        }
}
The content and fine structure of keratan and chondroitin/dermatan sulfate in normal human corneas and corneas affected by macular corneal dystrophies (MCD) types I and II were examined by fluorophore-assisted carbohydrate electrophoresis. Normal tissues (n = 11) contained 15 microg of keratan sulfate and 8 microg of chondroitin/dermatan sulfate per mg dry weight. Keratan sulfates consisted of approximately 4% unsulfated, 42% monosulfated, and 54% disulfated disaccharides with number of average… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 32 CITATIONS

Mechanisms of self-organization for the collagen fibril lattice in the human cornea.

  • Journal of the Royal Society, Interface
  • 2013
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Structural and biochemical aspects of keratan sulphate in the cornea

  • Cellular and Molecular Life Sciences
  • 2009
VIEW 5 EXCERPTS
CITES RESULTS & BACKGROUND
HIGHLY INFLUENCED

Biosynthesis of glycosaminoglycans: associated disorders and biochemical tests

  • Journal of Inherited Metabolic Disease
  • 2015
VIEW 1 EXCERPT
CITES BACKGROUND

Similar Papers

Loading similar papers…