Altered fibrin clot structure in the healthy relatives of patients with premature coronary artery disease.

Abstract

BACKGROUND A family history of premature coronary artery disease (CAD) is an independent cardiovascular risk factor. Fibrin clots composed of dense fiber networks are found in young CAD patients and may occur in the relatives of such individuals. METHODS AND RESULTS The ex vivo fibrin structure of 100 healthy male relatives of patients with premature CAD… (More)

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