Altered extracellular levels of DOPAC and HVA in the rat nucleus accumbens shell in response to sub-chronic nandrolone administration and a subsequent amphetamine challenge.

@article{Birgner2007AlteredEL,
  title={Altered extracellular levels of DOPAC and HVA in the rat nucleus accumbens shell in response to sub-chronic nandrolone administration and a subsequent amphetamine challenge.},
  author={Carolina Birgner and Anna M. S. Kindlundh-H{\"o}gberg and Fred J Nyberg and Lena Bergstr{\"o}m},
  journal={Neuroscience letters},
  year={2007},
  volume={412 2},
  pages={168-72}
}
Associated with acts of violence and polydrug use, abuse of anabolic androgenic steroids (AAS) is an increasing problem in society. The aim of the present study was to elucidate whether sub-chronic treatment with the AAS nandrolone decanoate affects dopamine release and dopamine metabolism in the rat nucleus accumbens shell, before and after an amphetamine challenge. Male Sprague-Dawley rats received daily i.m. injections of nandrolone decanoate (15 mg/kg) or vehicle for 14 days. On day 15, the… CONTINUE READING
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