Altered expression patterns of VEGF receptors in human diabetic retina and in experimental VEGF-induced retinopathy in monkey.

@article{Witmer2002AlteredEP,
  title={Altered expression patterns of VEGF receptors in human diabetic retina and in experimental VEGF-induced retinopathy in monkey.},
  author={Antonella N Witmer and Harriet G T Blaauwgeers and Herbert A. Weich and Kari Alitalo and Gijs F. J. M. Vrensen and Reinier Otto Schlingemann},
  journal={Investigative ophthalmology & visual science},
  year={2002},
  volume={43 3},
  pages={849-57}
}
PURPOSE The vascular endothelial growth factor (VEGF) family is involved in vascular leakage and angiogenesis in diabetic retinopathy (DR) in the eye, but may also have physiological functions. Based on the hypothesis that differential VEGF receptor (VEGFR) expression in the retina is an important determinant of effects of VEGF, this study was conducted to investigate VEGFR expression in the diabetic retina and in an experimental monkey model of VEGF-A-induced retinopathy. METHODS In retinas… CONTINUE READING
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