Altered expression of the p50 subunit of the NF-kappa B transcription factor complex in non-small cell lung carcinoma.

@article{Mukhopadhyay1995AlteredEO,
  title={Altered expression of the p50 subunit of the NF-kappa B transcription factor complex in non-small cell lung carcinoma.},
  author={T. C. Mukhopadhyay and J. L. A. Roth and Steven A. Maxwell},
  journal={Oncogene},
  year={1995},
  volume={11 5},
  pages={999-1003}
}
Recent studies have implicated a role for the p50 subunit of the NF-kappa B transcription factor complex in tumorigenesis. Therefore, we investigated the expression of the p50 subunit of the NF-kappa B transcription factor complex in paired normal and non-small cell lung carcinoma (NSCLC) tissues. Here we show that nine of 11 (81.8%) fresh NSCLC tissues expressed from two- to 20-fold higher levels of the p50 subunit than normal lung tissue. Thirteen NSCLC cell lines also exhibited high levels… CONTINUE READING

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