Altered expression of early cardiac marker genes in circulating cells of patients with hypertrophic cardiomyopathy.

@article{Kontaraki2007AlteredEO,
  title={Altered expression of early cardiac marker genes in circulating cells of patients with hypertrophic cardiomyopathy.},
  author={J. Kontaraki and F. Parthenakis and A. Patrianakos and I. Karalis and P. Vardas},
  journal={Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology},
  year={2007},
  volume={16 6},
  pages={
          329-35
        }
}
BACKGROUND Early cardiac marker genes, such as cardiac-specific homeobox (Csx/Nkx2.5), myocardin, homeodomain only protein, GATA4, and myocyte enhancer factor 2C, are thought to participate in cardiomyocyte differentiation and to contribute to heart hypertrophy in animal models. In this study, we investigated whether the expression of early cardiac genes is altered in the peripheral blood of patients with hypertrophic cardiomyopathy. METHODS Peripheral blood mononuclear cells were isolated… Expand
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