Altered expression of diabetes in BB/Wor rats by exposure to viral pathogens.

@article{Thomas1991AlteredEO,
  title={Altered expression of diabetes in BB/Wor rats by exposure to viral pathogens.},
  author={Valerie A Thomas and Bruce A. Woda and Eugene S. Handler and Dale L. Greiner and John P. Mordes and Aldo A. Rossini},
  journal={Diabetes},
  year={1991},
  volume={40 2},
  pages={255-8}
}
Autoimmune diabetes mellitus affects greater than 50% of diabetes-prone BB (DP BB) rats but less than 1% of diabetes-resistant BB (DR BB) rats. We report an outbreak of spontaneous diabetes among DR BB rats that coincided with serologic evidence of the onset of viral infection. This apparent link between a change in the environment and the expression of diabetes then led us to study the interaction of environmental exposure to viral pathogens in this disorder with virally seropositive and… CONTINUE READING
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