Altered expression of alpha-fetoprotein and albumin in early embryonic rat liver upon heat shock.


During rat liver development alpha-fetoprotein (AFP) and albumin (alb) are differentially regulated. Alpha-fetoprotein synthesis starts soon after fertilization whereas the earliest time albumin could be detected is day 17-18. However during normal development trace amounts of albumin mRNA could be detected on day 14 or 15. When 12-13 day old embryonic rat… (More)