Altered dynamics of DNA bases adjacent to a mismatch: a cue for mismatch recognition by MutS.

@article{Nag2007AlteredDO,
  title={Altered dynamics of DNA bases adjacent to a mismatch: a cue for mismatch recognition by MutS.},
  author={Nabanita Nag and B Jagadeeshwar Rao and Guruswamy Krishnamoorthy},
  journal={Journal of molecular biology},
  year={2007},
  volume={374 1},
  pages={39-53}
}
The structural deviations as well as the alteration in the dynamics of DNA at mismatch sites are considered to have a crucial role in mismatch recognition followed by its repair utilizing mismatch repair family proteins. To compare the dynamics at a mismatch and a non-mismatch site, we incorporated 2-aminopurine, a fluorescent analogue of adenine next to a G.T mismatch, a C.C mismatch, or an unpaired T, and at several other non-mismatch positions. Rotational diffusion of 2-aminopurine at these… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

Similar Papers

Loading similar papers…