Altered distribution of the nuclear receptor rarβ accompanies proliferation and differentiation changes caused by retinoic acid in Caco-2 cells

@article{McCormack1996AlteredDO,
  title={Altered distribution of the nuclear receptor rarβ accompanies proliferation and differentiation changes caused by retinoic acid in Caco-2 cells},
  author={Shirley A. McCormack and Mary Jane Viar and Larry Tague and Leonard R. Johnson},
  journal={In Vitro Cellular & Developmental Biology - Animal},
  year={1996},
  volume={32},
  pages={53-61}
}
All epithelial cells require retinoic acid for growth, maintenance, and differentiation. Although the epithelial cells that line the gastrointestinal tract are exposed to extreme retinoid concentration fluctuations in luminal fluid, whether proliferation and differentiation in these cells are significantly affected is not known. We have investigated this question using Caco-2 cells as a model because, although they are derived from a colon adenocarcinoma, they differentiate spontaneously in a… CONTINUE READING
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Effect of retinoid status on ct,13 and T retinoie acid receptor mRNA levels in various rat tissues

  • S. Kato, H. Mano, T Kumazawa
  • Biochem. J. 286:755-760;
  • 1992

In vivo and in vitro induction of "tissue" transglutaminase in rat hepatoeytes by retinoic acid

  • M Piaeentini, M. P. Ceru, L Dini
  • Bioehim. Biophys. Aeta
  • 1992

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