Altered distribution of aquaporin 5 and its C-terminal binding protein in the lacrimal glands of a mouse model for Sjögren's syndrome.

@article{Ohashi2008AlteredDO,
  title={Altered distribution of aquaporin 5 and its C-terminal binding protein in the lacrimal glands of a mouse model for Sj{\"o}gren's syndrome.},
  author={Yoshiki Ohashi and Kensei Tsuzaka and Tsutomu Takeuchi and Yasumasa Sasaki and Kazuo Tsubota},
  journal={Current eye research},
  year={2008},
  volume={33 8},
  pages={621-9}
}
PURPOSE To investigate the distribution and expression of aquaporin 5 (AQP5) and its C-terminal binding protein in the apical membrane of the lacrimal glands (LGs) in a mouse model for Sjogren's syndrome (SS). METHODS The LGs of NOD mice (mouse model for SS) and ICR mice (normal control) were homogenized and delivered into the affinity columns bound to synthetic AQP5 C-terminal peptide. The eluates were analyzed by electrophoresis and liquid chromatography mass spectrometry/mass spectrometry… CONTINUE READING

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