Altered cytoskeletal structure of smooth muscle cells in ureteropelvic junction obstruction.

  title={Altered cytoskeletal structure of smooth muscle cells in ureteropelvic junction obstruction.},
  author={Giuseppina Cutroneo and Salvatore Arena and Giuseppe Anastasi and Raimondo Maximillian Cervellione and Silvia Grimaldi and Debora Di Mauro and Francesco Speciale and Francesco Arena and Vincenzo Di Benedetto and Angelo Favaloro and Carlo Magno},
  journal={The Journal of urology},
  volume={185 6},
PURPOSE Ureteropelvic junction obstruction is one of the most common causes of hydronephrosis in children. A malfunction of smooth muscle cells is believed to be the underlying mechanism causing obstruction. We investigated the expression of some integrins, talin and β-dystroglycan, considered the main compound of smooth muscle cell cytoskeleton, and active caspase 3 at the level of the ureteropelvic junction obstruction. MATERIALS AND METHODS Specimens were obtained at pyeloplasty in 12… CONTINUE READING


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