Altered cortical-cerebellar circuits during verbal working memory in essential tremor.

@article{Passamonti2011AlteredCC,
  title={Altered cortical-cerebellar circuits during verbal working memory in essential tremor.},
  author={Luca Passamonti and Fabiana Novellino and Antonio Cerasa and Carmelina Chiriaco and Federico Rocca and Maria Stella Matina and Francesco Fera and Aldo Quattrone},
  journal={Brain : a journal of neurology},
  year={2011},
  volume={134 Pt 8},
  pages={2274-86}
}
Essential tremor is a common neurological disorder characterized by motor and cognitive symptoms including working memory deficits. Epidemiological research has shown that patients with essential tremor are at a higher risk to develop dementia relative to age-matched individuals; this demonstrates that cognitive impairments reflect specific, although poorly understood, disease mechanisms. Neurodegeneration of the cerebellum has been implicated in the pathophysiology of essential tremor itself… CONTINUE READING