Altered consciousness states and endogenous psychoses: a common molecular pathway?

  title={Altered consciousness states and endogenous psychoses: a common molecular pathway?},
  author={Jorge Ciprian-Ollivier and Marcelo G Cetkovich-Bakmas},
  journal={Schizophrenia Research},

A Comparative Review of the Neuro - Psychopharmacology of Hallucinogen - Induced Altered States of Consciousness: The Uniqueness of Some Hallucinogens

More detailed scientific research should be performed to understand the basic and real mechanisms of H - ASCs, to comprehend and unravel the mystery of human m ind and consciousness, since scientific medical research on hallucinogens has been legalized since 1992.

Ayahuasca, dimethyltryptamine, and psychosis: a systematic review of human studies

Individuals with a personal or family history of any psychotic illness or nonpsychotic mania should avoid hallucinogen intake.

Neuropharmacology of N,N-dimethyltryptamine

Risk assessment of ritual use of oral dimethyltryptamine (DMT) and harmala alkaloids.

A decoction of DMT and harmala alkaloids used in religious ceremonies has a safety margin comparable to codeine, mescaline or methadone, and there was no evidence that ayahuasca has substantial or persistent abuse potential.

Alcaloides e o chá de ayahuasca: uma correlação dos "estados alterados da consciência" induzido por alucinógenos

Among the numerous hallucinogenic plants utilized by indigenous populations of the Amazon Basin, perhaps none is as interesting or complex in terms of botany, chemistry or ethnography as the

A mood disorder episode with an onset under chronic cannabis consumption and accompanied with psychotic features immediately after N, N-Dimethyltryptamine (DMT) use: a case report -

, N-dimethyltryptamine (DMT) is a serotonin agonist hallucinogen, similar to lysergic acid diethylamide (LSD). Syntetic production of DMT as well as extraction from several plants of South American

Toxicological Aspects and Determination of the Main Components of Ayahuasca: A Critical Review

This paper will perform a comprehensive and critical review on the analytical methods available for their determination in biological and non-biological specimens, with special focus on instrumental developments and sample preparation approaches.

Phenomenology of N,N-Dimethyltryptamine use : a thematic analysis

Abstract—N,N-dimethyltryptamine (DMT) is an endogenous hallucinogeniccompound in the same chemical class as the more common psilocybin and theneurotransmitter serotonin. Despite previous experimental



Increased excretion of dimethyltryptamine and certain features of psychosis: a possible association.

The excretion of the hallucinogen dimethyltryptamine (DMT) and its precursor N-methyltryptamine (NMT) was studied among 74 recently admitted psychiatric patients and 19 normal persons. Both compounds

Detection of Psychotomimetic N,N-Dimethylated Indoleamines in the Urine of Four Schizophrenic Patients

On the basis of their previous work indicating that tryptamine appeared in increased concentrations in the urine before and during the activation of psychotic symptoms, they suggested that under loading conditions the formation of various N,N-dimethylated indoleamines might be facilitated in the body.

Dreams, hallucinogenic drug states, and schizophrenia: a psychological and biological comparison.

  • L. Fischman
  • Psychology, Medicine
    Schizophrenia bulletin
  • 1983
In the present article, certain fundamental areas of convergence between the three states are described and current neurophysiological theories of dream and hallucinogenic drug states are presented, with emphasis upon serotonin neurotransmission.

Dose-response study of N,N-dimethyltryptamine in humans. I. Neuroendocrine, autonomic, and cardiovascular effects.

Dimethyltryptamine can be administered safely to experienced hallucinogen users and dose-response data generated for several measures hypothesized under serotonergic modulatory control may prove useful in psychopharmacological investigations of drug-induced and endogenous alterations in brain function.

The psychedelic model of schizophrenia: the case of N,N-dimethyltryptamine.

The authors review the research on DMT as a possible "schizotoxin" and conclude that more data are necessary before the validity of this theory can be determined.

A Longitudinal Study of Urinary Excretion of N,N,-Dimethyltryptamine in Psychotic Patients

It is suggested that the extracerebral production of DMT (as measured by its urinary excretion) does not provoke the experience of hallucinations in psychotic patients.