Altered cerebral perfusion measured by SPECT in relatives of patients with schizophrenia. Correlations with memory and P300.

@article{Blackwood1999AlteredCP,
  title={Altered cerebral perfusion measured by SPECT in relatives of patients with schizophrenia. Correlations with memory and P300.},
  author={Douglas H. R. Blackwood and Mike F. Glabus and J T Dunan and Ronan E O'Carroll and Walter J. Muir and Klaus P. Ebmeier},
  journal={The British journal of psychiatry : the journal of mental science},
  year={1999},
  volume={175},
  pages={
          357-66
        }
}
BACKGROUND Genetic studies in schizophrenia are hampered by the complex heterogeneous clinical phenotype. Biological variables identified as trait markers of risk could clarify the mode of inheritance, define clinical subgroups and provide clues about aetiology. AIMS To use single photon emission computed tomography (SPECT) to compare brain perfusion maps in patients with schizophrenia (n = 19), their asymptomatic 'high-risk' relatives (n = 36) and control subjects (n = 34) and to examine the… CONTINUE READING
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