Altered cell fate in LiCl-treated sea urchin embryos.

  title={Altered cell fate in LiCl-treated sea urchin embryos.},
  author={C. Nocente-McGrath and R. McIsaac and S. Ernst},
  journal={Developmental biology},
  volume={147 2},
  • C. Nocente-McGrath, R. McIsaac, S. Ernst
  • Published 1991
  • Biology, Medicine
  • Developmental biology
  • Endo16 is a lineage-specific protein expressed during embryogenesis in the sea urchin, Strongylocentrotus purpuratus. [...] Key Result Our results show that treatment with LiCl causes increased steady-state levels of Endo16 transcripts. An increase in the number of endodermal cells in treated embryos demonstrates a change in cell lineage. In addition, we observed a delay in development of lithium-treated embryos that is accompanied by a delay in the expression of a late class histone H2B gene.Expand Abstract
    51 Citations

    Figures, Tables, and Topics from this paper.

    Specification of endoderm in the sea urchin embryo
    • 8
    • PDF
    Ca(2+) in specification of vegetal cell fate in early sea urchin embryos.
    • I. Yazaki
    • Medicine, Biology
    • The Journal of experimental biology
    • 2001
    • 14
    Early gene expression along the animal-vegetal axis in sea urchin embryoids and grafted embryos.
    • 22
    How to grow a gut: ontogeny of the endoderm in the sea urchin embryo
    • G. Wessel, A. Wikramanayake
    • Medicine, Biology
    • BioEssays : news and reviews in molecular, cellular and developmental biology
    • 1999
    • 22
    • PDF
    Nuclear beta-catenin is required to specify vegetal cell fates in the sea urchin embryo.
    • 419


    Developmental time, cell lineage, and environment regulate the newly synthesized proteins in sea urchin embryos.
    • 19
    • PDF
    Effects of cordycepin and cell dissociation on the synthesis of H1 histone by sea urchin embryos.
    • 7
    Endo16, a lineage-specific protein of the sea urchin embryo, is first expressed just prior to gastrulation.
    • 72
    • PDF
    Lithium-induced respecification of pattern in Xenopus laevis embryos
    • 236
    Lithium evokes expression of vegetal-specific molecules in the animal blastomeres of sea urchin embryos.
    • B. Livingston, F. Wilt
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 1989
    • 87
    • PDF
    Simultaneous expression of early and late histone messenger RNAs in individual cells during development of the sea urchin embryo.
    • 22
    Histone gene expression: progeny of isolated early blastomeres in culture make the same change as in the embryo.
    • 16