Altered bivalent positioning in metaphase I human spermatocytes from Robertsonian translocation carriers

@article{Sol2016AlteredBP,
  title={Altered bivalent positioning in metaphase I human spermatocytes from Robertsonian translocation carriers},
  author={Mireia Colom Sol{\'e} and J. J. Cuadrado Blanco and O. A. M{\'a}rquez Valero and Laia Verg{\'e}s and Francesca Vidal and Zaida Sarrate},
  journal={Journal of Assisted Reproduction and Genetics},
  year={2016},
  volume={34},
  pages={131-138}
}
PurposeThe study aims to determine whether there is an altered bivalent positioning in metaphase I human spermatocytes from Robertsonian translocation carriers.MethodsMetaphase I human spermatocytes from three 45,XY,der(13;14)(q10;q10) individuals and a 45,XY,der(14;15)(q10;q10) individual were analyzed. Proximity relationships of bivalents were established by analyzing meiotic preparations combining Leishman staining and multiplex-FISH procedures. Poisson regression model was used to determine… CONTINUE READING
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