Altered artery mechanics and structure in monocrotaline pulmonary hypertension.

  title={Altered artery mechanics and structure in monocrotaline pulmonary hypertension.},
  author={D Langleben and John L Szarek and Janice T. Coflesky and Rosemary C. Jones and Lynne M. Reid and John N. Evans},
  journal={Journal of applied physiology},
  volume={65 5},
Pulmonary hypertension in rats, induced by an injection of monocrotaline, is associated with changes in the wall structure of the pulmonary arterial bed. We have studied the effects of this remodeling on mechanical properties of cylindrical pulmonary artery segments from rats 21 days after monocrotaline (MCT) injection. Resting and active (KCl induced) circumference-tension relationships were established for segments of extrapulmonary and intrapulmonary arteries isolated from the hilum and the… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-7 of 7 extracted citations

Similar Papers

Loading similar papers…