Altered alveolar mechanics in the acutely injured lung.

  title={Altered alveolar mechanics in the acutely injured lung.},
  author={Henry J Schiller and Ulysse G McCann and David Edward Carney and Louis A. Gatto and Jay M Steinberg and Gary F. Nieman},
  journal={Critical care medicine},
  volume={29 5},
OBJECTIVES Alterations in alveolar mechanics (i.e., the dynamic change in alveolar size during tidal ventilation) are thought to play a critical role in acute lung injuries such as acute respiratory distress syndrome (ARDS). In this study, we describe and quantify the dynamic changes in alveolar mechanics of individual alveoli in a porcine ARDS model by direct visualization using in vivo microscopy. DESIGN Prospective, observational, controlled study. SETTING University research laboratory… CONTINUE READING


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