Altered Regulation of type 3 Na+/H+ exchanger, type 1 Na+/HCO3- cotransporter, and Na+,K+-ATPase in the Kidney of Rats with Experimental Rhabdomyolysis

@article{Ma2007AlteredRO,
  title={Altered Regulation of type 3 Na+/H+ exchanger, type 1 Na+/HCO3- cotransporter, and Na+,K+-ATPase in the Kidney of Rats with Experimental Rhabdomyolysis},
  author={S. Ma and E. Bae and Jongun Lee and S. Kim and S. Z. Kim and K. Choi and Soo Kim},
  journal={Electrolytes \& Blood Pressure : E \& BP},
  year={2007},
  volume={5},
  pages={55 - 61}
}
  • S. Ma, E. Bae, +4 authors Soo Kim
  • Published 2007
  • Medicine
  • Electrolytes & Blood Pressure : E & BP
Metabolic acidosis was shown to correlate with deterioration of renal function in patients with rhabdomyolysis. The present study was aimed to investigate whether the changes of type 3 Na+/H+ exchanger (NHE3), type 1 Na+/HCO3- cotransporter (NBC1), and Na+,K+-ATPase α1 subunit may play a role in the pathogenesis of metabolic acidosis in glycerol-induced experimental rhabdomyolysis. Male Sprague-Dawley rats were deprived of fluid intake for 24 hours, and then were injected with 50% glycerol in… Expand
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References

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