Altered RNA editing in mice lacking ADAR2 autoregulation.

  title={Altered RNA editing in mice lacking ADAR2 autoregulation.},
  author={Yi Feng and Christopher L Sansam and Minati Singh and Ronald B. Emeson},
  journal={Molecular and cellular biology},
  volume={26 2},
ADAR2 is a double-stranded-RNA-specific adenosine deaminase involved in the editing of mammalian RNAs by the site-selective conversion of adenosine to inosine. Previous studies from our laboratory have demonstrated that ADAR2 can modify its own pre-mRNA to create a proximal 3' splice site containing a noncanonical adenosine-inosine dinucleotide. Alternative… CONTINUE READING