Altered Neurogranin Phosphorylation and Protein Levels Are Associated with Anxiety-and Depression-Like Behaviors in Rats Following Forced Swim Stress

@inproceedings{Li2014AlteredNP,
  title={Altered Neurogranin Phosphorylation and Protein Levels Are Associated with Anxiety-and Depression-Like Behaviors in Rats Following Forced Swim Stress},
  author={Huanhuan Li and Wenjuan Lin and Junfa Li and Weiwen Wang},
  year={2014}
}
Here we tested the hypothesis that stress-induced alterations in Neurogranin (Ng) synthesis and/ or utilization might underlie stress-related depression and anxiety. Rats were randomly divided into five conditions: chronic swim stress (CS), acute swim stress (AS), and three control groups. The CS group was exposed to daily swim stress (5 min/day) for 14 consecutive days, the AS group received a single swim stress, and control groups were maintained in a stress-free condition. Both before and… CONTINUE READING