Altered Hepcidin Expression is Part of the Choroid Plexus Response to IL-6/Stat3 Signaling Pathway in Normal Aging Rats

@inproceedings{Chongbin2014AlteredHE,
  title={Altered Hepcidin Expression is Part of the Choroid Plexus Response to IL-6/Stat3 Signaling Pathway in Normal Aging Rats},
  author={L. Chongbin and W. Rui and W. Chunyan and C. Hu and D. Qifeng},
  year={2014}
}
Accumulating evidence has revealed that brain iron concentrations increase with aging, and the choroid plexus may be at the basis of iron-mediated toxicity and the increase in inflammation and oxidative stress that occurs with aging. However, nothing is known concerning the correlation between the IL-6/Stat3 signaling pathway and the levels of hepcidin expression at the choroid plexus (CP) in normal aging. The morphological modifications as a function of aging were investigated and the present… Expand
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SHOWING 1-10 OF 29 REFERENCES
Altered iron metabolism is part of the choroid plexus response to peripheral inflammation.
Interacting signals in the control of hepcidin expression
Low hepcidin accounts for the proinflammatory status associated with iron deficiency.
IL-6 - STAT-3 - hepcidin: linking inflammation to the iron metabolism.
Post‐transcriptional expression of DMT1 in the heart of rat
Regulation of hepcidin transcription by interleukin-1 and interleukin-6.
STAT3 signaling within hepatocytes is required for anemia of inflammation in vivo
Hepcidin regulation by innate immune and infectious stimuli.
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