Altered Heavy Metals and Transketolase Found in Autistic Spectrum Disorder

@article{Obrenovich2011AlteredHM,
  title={Altered Heavy Metals and Transketolase Found in Autistic Spectrum Disorder},
  author={Mark E. Obrenovich and Raymond J. Shamberger and Derrick Lonsdale},
  journal={Biological Trace Element Research},
  year={2011},
  volume={144},
  pages={475-486}
}
Autism and autism spectrum disorder (ASD) are developmental brain disorders with complex, obscure, and multifactorial etiology. Our recent clinical survey of patient records from ASD children under the age of 6 years and their age-matched controls revealed evidence of abnormal markers of thiol metabolism, as well as a significant alteration in deposition of several heavy metal species, particularly arsenic, mercury, copper, and iron in hair samples between the groups. Altered thiol metabolism… CONTINUE READING
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