Altered HLA-G transcription in pre-eclampsia is associated with allele specific inheritance: possible role of the HLA-G gene in susceptibility to the disease

@article{Obrien2001AlteredHT,
  title={Altered HLA-G transcription in pre-eclampsia is associated with allele specific inheritance: possible role of the HLA-G gene in susceptibility to the disease},
  author={Marilyn O'brien and Terri McCarthy and Dagan Jenkins and Priyanka Paul and Jean Dausset and Edgardo D. Carosella and Philippe Moreau},
  journal={Cellular and Molecular Life Sciences CMLS},
  year={2001},
  volume={58},
  pages={1943-1949}
}
Pre-eclampsia is a disorder of human pregnancy occuring in 5-10 % of all births, and represents the leading cause of infant morbidity and mortality and maternal death. In pre-eclampsia, invasion of fetal trophoblasts into maternal arteries during early pregnancy is shallow or absent. Here we examined the hypothesis that HLA-G, a non-classical class I HLA… CONTINUE READING