Altered Glutamatergic Metabolism Associated with Punctate White Matter Lesions in Preterm Infants

@inproceedings{Wisnowski2013AlteredGM,
  title={Altered Glutamatergic Metabolism Associated with Punctate White Matter Lesions in Preterm Infants},
  author={Jessica L. Wisnowski and Stefan Blueml and Lisa B. Paquette and Elizabeth M. Zelinski and Marvin D. Nelson and Michael J. Painter and Hanna Damasio and Floyd Gilles and Ashok Panigrahy},
  booktitle={PloS one},
  year={2013}
}
Preterm infants (∼10% of all births) are at high-risk for long-term neurodevelopmental disabilities, most often resulting from white matter injury sustained during the neonatal period. Glutamate excitotoxicity is hypothesized to be a key mechanism in the pathogenesis of white matter injury; however, there has been no in vivo demonstration of glutamate… CONTINUE READING