Altered E-NTPDase/E-ADA activities and CD39 expression in platelets of sickle cell anemia patients.

Abstract

Sickle cell anemia (SCA) is a hemoglobinopathy characterized by hemolysis and vaso-occlusions caused by rigidly distorted red blood cells. Sickle cell crisis is associated with extracellular release of nucleotides and platelets, which are critical mediators of hemostasis participating actively in purinergic thromboregulatory enzymes system.This study aimed… (More)
DOI: 10.1016/j.biopha.2016.02.009

Topics

Cite this paper

@article{Castilhos2016AlteredEA, title={Altered E-NTPDase/E-ADA activities and CD39 expression in platelets of sickle cell anemia patients.}, author={L{\'i}via Gelain Castilhos and Pedro Henrique Doleski and Stephen Adeniyi Adefegha and Lara Vargas Becker and Jader Betch Ruchel and Daniela Bitencourt Rosa Leal}, journal={Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie}, year={2016}, volume={79}, pages={241-6} }