Altered D-chiro-inositol urinary clearance in women with polycystic ovary syndrome.

@article{Baillargeon2006AlteredDU,
  title={Altered D-chiro-inositol urinary clearance in women with polycystic ovary syndrome.},
  author={Jean-Patrice Baillargeon and Evanthia Diamanti-Kandarakis and Richard E. Ostlund and Teimuraz Apridonidze and Maria J. Iuorno and John E. Nestler},
  journal={Diabetes care},
  year={2006},
  volume={29 2},
  pages={
          300-5
        }
}
  • Jean-Patrice Baillargeon, Evanthia Diamanti-Kandarakis, +3 authors John E. Nestler
  • Published in Diabetes care 2006
  • Medicine
  • OBJECTIVE Evidence suggests that some actions of insulin are effected by inositolphosphoglycan (IPG) mediators. We hypothesize that a deficiency in D-chiro-inositol (DCI) and/or a DCI-containing IPG (DCI-IPG) may contribute to insulin resistance in humans. RESEARCH DESIGN AND METHODS To assess this possibility in polycystic ovary syndrome (PCOS), we determined insulin sensitivity (Si by frequently sampled intravenous glucose tolerance test), plasma and urinary DCI and myo-inositol (MYO… CONTINUE READING

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