Alterations of the perivascular dystrophin-dystroglycan complex following brain lesions: an immunohistochemical study in rats.

@article{Klmn2011AlterationsOT,
  title={Alterations of the perivascular dystrophin-dystroglycan complex following brain lesions: an immunohistochemical study in rats.},
  author={Mih{\'a}ly K{\'a}lm{\'a}n and Judit Mahalek and Andr{\'a}s Adorj{\'a}n and Istv{\'a}n Adorj{\'a}n and K{\'a}roly P{\'o}csai and Zsolt Bagyura and Sam Sadeghian},
  journal={Histology and histopathology},
  year={2011},
  volume={26 11},
  pages={1435-52}
}
Dystroglycan is a laminin receptor, which with dystrophins and other components forms the dystrophin-dystroglycan complex. It has an important role in the formation of gliovascular connections, cerebral vascularisation and blood-brain barrier. Dystroglycan consists of two sub-units, α and β. Previous studies demonstrated that the β-dystroglycan immunoreactivity of cerebral vessels temporarily disappeared in the area adjacent to the lesion, whereas the vascular laminin which is not… CONTINUE READING