Alterations of the murine gut microbiome in allergic airway disease are independent of surfactant protein D

Abstract

BACKGROUND SP-D is an important host defense lectin in innate immunity and SP-D deficient mice show several abnormal immune effects and are susceptible to allergen-induced airway disease. At the same time, host microbiome interactions play an important role in the development of allergic airway disease, and alterations to gut microbiota have been linked to… (More)
DOI: 10.1016/j.heliyon.2017.e00262

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