Alterations of the gut microbiota in high-fat diet mice is strongly linked to oxidative stress

@article{Qiao2012AlterationsOT,
  title={Alterations of the gut microbiota in high-fat diet mice is strongly linked to oxidative stress},
  author={Yi Qiao and J. H. Sun and Yinyi Ding and Guowei Le and Yonghui Shi},
  journal={Applied Microbiology and Biotechnology},
  year={2012},
  volume={97},
  pages={1689-1697}
}
Alterations of the gut microbiota induced by diet exert a strong influence on the development of metabolic syndrome. In this study, we prove the hypothesis that the long-term high-fat diet (HFD) may influence gut microbiota directly and/or indirectly by changing the redox state. Lipoic acid (LA), as a universal antioxidant, was used to improve the redox state. Reactive oxygen species (ROS), total antioxidant capacity (T-AOC), and malondialdehyde (MDA) were analyzed to profile oxidative stress… CONTINUE READING
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