Alterations of skeletal muscle in chronic heart failure.

@article{Drexler1992AlterationsOS,
  title={Alterations of skeletal muscle in chronic heart failure.},
  author={Heinz Drexler and Ulf Riede and Thomas F. M{\"u}nzel and Helma Koenig and Edgar Funke and Herwig Just},
  journal={Circulation},
  year={1992},
  volume={85 5},
  pages={1751-9}
}
BACKGROUND The present study was designed to define the prevalence and characteristics of skeletal muscle alterations in patients with chronic heart failure (CHF) and their relation to exercise capacity. METHODS AND RESULTS The ultrastructure of skeletal muscle was analyzed by ultrastructural morphometry in 57 patients with CHF and 18 healthy controls. The volume density of mitochondria (Vvm) and the surface density (Svmc) of mitochondrial cristae were evaluated as a structural correlate of… CONTINUE READING
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