Alterations of red blood cell metabolome during cold liquid storage of erythrocyte concentrates in CPD-SAGM.

@article{Gevi2012AlterationsOR,
  title={Alterations of red blood cell metabolome during cold liquid storage of erythrocyte concentrates in CPD-SAGM.},
  author={Federica Gevi and Angelo D'Alessandro and Sara Rinalducci and Lello Zolla},
  journal={Journal of proteomics},
  year={2012},
  volume={76 Spec No.},
  pages={168-80}
}
Erythrocyte concentrates for transfusion purposes represent a life-saving therapeutics of primary relevance in the clinical setting. However, efforts have been continuously proposed to improve safety and efficacy of long-term stored red blood cells. By means of liquid chromatography coupled with Q-TOF mass spectrometry, we were able to perform an untargeted metabolomics analysis in order to highlight metabolic species (i.e. low molecular biochemicals including sugars, lipids, nucleotides… CONTINUE READING