Alterations of platelet biochemical and functional properties in newly diagnosed type 1 diabetes: a role in cardiovascular risk?

@article{Vignini2011AlterationsOP,
  title={Alterations of platelet biochemical and functional properties in newly diagnosed type 1 diabetes: a role in cardiovascular risk?},
  author={Arianna Vignini and Cinzia Moroni and Laura Nanetti and Francesca Raffaelli and Annamaria Cester and Orazio Gabrielli and Valentino Cherubini and Laura Mazzanti},
  journal={Diabetes/metabolism research and reviews},
  year={2011},
  volume={27 3},
  pages={
          277-85
        }
}
BACKGROUND The involvement of platelets in the pathogenesis of diabetic vascular complications is supported by several studies. Type 1 diabetic (T1D) platelets show increased adhesiveness and aggregation related to a modification of nitric oxide synthase activity. Moreover, different cell types from diabetic patients showed a decreased membrane Na(+) /K(+) -ATPase activity, which might be involved in diabetic complications. The aim of this study was to investigate whether T1D at onset is able… CONTINUE READING

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