Alterations of microRNAs throughout the malignant evolution of cutaneous squamous cell carcinoma: the role of miR-497 in epithelial to mesenchymal transition of keratinocytes

@article{Mizrahi2018AlterationsOM,
  title={Alterations of microRNAs throughout the malignant evolution of cutaneous squamous cell carcinoma: the role of miR-497 in epithelial to mesenchymal transition of keratinocytes},
  author={Aya Mizrahi and Aviv Barzilai and Devorah Gur-Wahnon and Iddo Z. Ben-Dov and S Glassberg and Tal Meningher and E Elharar and Moamen Masalha and Jasmine Jacob-Hirsch and Hilla Tabibian-Keissar and Iris Barshack and Jason Roszik and Raya Leibowitz-Amit and Yechezkel Sidi and Dror Avni},
  journal={Oncogene},
  year={2018},
  volume={37},
  pages={218-230}
}
Skin carcinogenesis is known to be a multi-step process with several stages along its malignant evolution. We hypothesized that transformation of normal epidermis to cutaneous squamous cell carcinoma (cSCC) is causally linked to alterations in microRNAs (miRNA) expression. For this end we decided to evaluate their alterations in the pathologic states ending… CONTINUE READING