Alterations of cognitive functions induced by exogenous application of thyroid hormones in healthy men: a double-blind cross-over study using event-related brain potentials.

@article{Mnte2001AlterationsOC,
  title={Alterations of cognitive functions induced by exogenous application of thyroid hormones in healthy men: a double-blind cross-over study using event-related brain potentials.},
  author={Thomas F M{\"u}nte and C Radamm and S{\"o}nke Johannes and Georg Brabant},
  journal={Thyroid : official journal of the American Thyroid Association},
  year={2001},
  volume={11 4},
  pages={385-91}
}
The influence of experimentally induced subclinical hyperthyroidism on cognitive functions was tested using exogenous thyroxine or placebo. In a double-blind cross-over design, 24 healthy young men received either 300 microg of levothyroxine or placebo for two consecutive 3-week periods. Determination of thyrotropin (TSH), total triiodothyronine (T3), thyroxine (T4), and sex hormone binding globulin (SHBG) confirmed the induction of subclinical hyperthyroidism. Three weeks after treatment with… CONTINUE READING