Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas.

@article{Smith2000AlterationsOC,
  title={Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas.},
  author={Jay Smith and Arie Perry and Thomas J. Borell and Hun Kyung Lee and J R O'fallon and Sandra M Hosek and David W Kimmel and Allan Yates and Peter C. Burger and Bernd Walter Scheithauer and R. Brian Jenkins},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2000},
  volume={18 3},
  pages={636-45}
}
PURPOSE A recent report suggests that alterations of chromosome arms 1p and 19q are associated with chemotherapeutic response and overall survival in anaplastic oligodendroglioma patients treated with procarbazine, lomustine, and vincristine chemotherapy. We set out to further clarify the diagnostic and prognostic implications of these alterations in a broader set of diffuse gliomas, including astrocytic neoplasms and low-grade oligodendrogliomas. PATIENTS AND METHODS Fluorescence in situ… CONTINUE READING
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