Alterations of E-cadherin, α-catenin and β-catenin expression in neuroendocrine tumors of the gastrointestinal tract

@article{Li2002AlterationsOE,
  title={Alterations of E-cadherin, α-catenin and β-catenin expression in neuroendocrine tumors of the gastrointestinal tract},
  author={Chiun Chei Li and Bing Xu and Mitsuyoshi Hirokawa and Zhirong Qian and Katsuhiko Yoshimoto and Hidehisa Horiguchi and Takashi Tashiro and Toshiaki Sano},
  journal={Virchows Archiv},
  year={2002},
  volume={440},
  pages={145-154}
}
Neuroendocrine tumors (NETs) of the gastrointestinal tract comprise a heterogeneous group of neoplasms arising from the diffuse neuroendocrine system. These tumors strongly differ from each other on the basis of different pathogenetic, clinical, functional, histological, and prognostic patterns. Previous studies have shown that abnormal and reduced expression of the E-cadherin/catenin complex in several human cancers is associated with tumor dedifferentiation, advanced clinical stages, and poor… CONTINUE READING

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Immunohistochemical analysis of the proliferative activity of neuroendocrine tumors from various organs . Are there indications for a neuroendocrine tumor - carcinoma sequence ?

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Virchows Arch • 2001

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