Alterations of Cytological and Karyological Profi le of Human Mesenchymal Stem Cells during in Vitro Culturing

@article{Grigorian2010AlterationsOC,
  title={Alterations of Cytological and Karyological Profi le of Human Mesenchymal Stem Cells during in Vitro Culturing},
  author={Anahit Grigorian and Peter Kruglyakov and U. A. Taminkina and Olga A Efimova and Anna A. Pendina and A. V. Voskresenskaya and Tatanya V Kuznetsova and D. G. Polyntsev},
  journal={Bulletin of Experimental Biology and Medicine},
  year={2010},
  volume={150},
  pages={125-130}
}
Transplantation of human bone marrow mesenchymal stem cells is considered as a promising therapeutic approach to the therapy of many diseases. However, the problem of possible alterations of the properties of mesenchymal stem cells during their expansion in in vitro cultures before transplantation is not solved. In our study, one of two hundred examined cultures of mesenchymal stem cell cultures derived from donors without bone marrow pathologies and developed under standard culturing… CONTINUE READING

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