Alterations in transcription clusters underlie development of bladder cancer along papillary and nonpapillary pathways

Abstract

Bladder cancer develops in the urothelial lining from intraurothelial preneoplasia via two pathways, papillary and nonpapillary, which correspond to nonaggressive and aggressive forms of the disease. Because these two forms of cancer may develop via distinct molecular events, we examined the gene expression patterns in the development of bladder cancer from… (More)
DOI: 10.1038/labinvest.3700250

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