Alterations in tight junctions differ between primary biliary cirrhosis and primary sclerosing cholangitis.

Abstract

Tight junctions (TJ) of biliary epithelial cells (BEC) and hepatocytes prevent bile regurgitation from the biliary tract. Alterations in these TJs may participate in chronic cholestatic liver diseases such as primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC). We examined the localization of 2 TJ proteins, ZO-1 and 7H6, in these… (More)

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Cite this paper

@article{Sakisaka2001AlterationsIT, title={Alterations in tight junctions differ between primary biliary cirrhosis and primary sclerosing cholangitis.}, author={Shotaro Sakisaka and Takeo Kawaguchi and Eitaro Taniguchi and Sachiyo Hanada and Kurumi Sasatomi and Hiroshi Koga and Masaru Harada and Ryojiro Kimura and Michio Sata and Norimasa Sawada and Masatomo Mori and Satoru Todo and Toshihiko Kurohiji}, journal={Hepatology}, year={2001}, volume={33 6}, pages={1460-8} }