Alterations in the regulatory region of the human papillomavirus type 6 genome are generated during propagation in Escherichia coli.

@article{Kasher1988AlterationsIT,
  title={Alterations in the regulatory region of the human papillomavirus type 6 genome are generated during propagation in Escherichia coli.},
  author={M S Kasher and Ann Roman},
  journal={Journal of virology},
  year={1988},
  volume={62 9},
  pages={3295-300}
}
We analyzed the long control regions (LCRs) of seven human papillomavirus type 6b (HPV-6b) clones, which contained prototype HPV-6b sequences recloned into various plasmid vectors and propagated in different strains of Escherichia coli. Southern blot analysis and DNA sequencing demonstrated three different sequences, each distinct from the published… CONTINUE READING