Alterations in the protein composition of maturing phagosomes.

@article{Pitt1992AlterationsIT,
  title={Alterations in the protein composition of maturing phagosomes.},
  author={Allyson S. Pitt and Luis S. Mayorga and Philip D. Stahl and Alan L. Schwartz},
  journal={The Journal of clinical investigation},
  year={1992},
  volume={90 5},
  pages={
          1978-83
        }
}
We investigated the protein composition of J774-E clone macrophage phagosomes isolated at different stages of phagolysosome biogenesis. Phagosomes formed by internalizing antibody-coated Staphylococcus aureus for 3 min followed by chase for 0, 4, 9, or 15 min were isolated by density gradient centrifugation. Enrichment and purity of the phagosome preparations were quantitated by radiolabeled ligand recovery, enzyme markers, and electron microscopy. One-dimensional SDS-PAGE analyses of the… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 77 CITATIONS, ESTIMATED Infinity% COVERAGE

77 Citations

02468'94'99'05'11'17
Citations per Year
Semantic Scholar estimates that this publication has 77 citations based on the available data.

See our FAQ for additional information.

Similar Papers

Loading similar papers…